Product.
DNA Curtains Flowcell.
DNA Curtains Flow Cell
Create new insights into protein–DNA interactions with our DNA Curtains Flow Cell. The user-friendly, reusable device enables acquisition of dynamic and kinetic data with single-molecule resolution and high experimental throughput.
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The system consists of microfluidic flow channels with nanobarrier arrays that support efficient formation of DNA curtains, allowing simultaneous imaging of hundreds of individual DNA molecules in a single measurement.
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Minimal sample volumes are required, typically microliter-scale at nanomolar protein concentrations, reducing consumption of valuable reagents.
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The flow cell is compatible with standard commercial fluorescence microscope stages, enabling straightforward integration into existing setups.
Physical specifications
Width
30 mm
Length
40 mm
Depth
9 mm
Weight
38 g
Number of channels
6
Compatibility
Microscope type
Standard TIRF Microscope
Microfluidic pump system
Fluid pulling
Channel
Channel dimensions
0.04 x 0.4 x 30 mm
Channel volume
0,5 μL
Typical flow rate
1 μL/min
Channel dead volume
2 μL
Nanostructures
Nanostructure material
Gold or titanium
DNA attachment type
Single or double tethered
Number of tethers
100+ per FOV
Workflow details
Experiment set up time
40 minutes
Surface preservation
Lipid bilayer
DNA Length
20-60 kbp
Applications